Cas No. |
Product name |
905586-69-8 |
AZ960 |
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AZ 960 is a novel ATP competitive JAK2 inhibitor with IC50 and Ki of <3 nM and 0.45 nM, 3-fold selectivity of AZ960 for JAK2 over JAK3. |
1198300-79-6 |
PRT062070(Cerdulatnib) |
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Cerdulatinib(PRT-062070; PRT2070) is an novel oral dual Syk/JAK inhibitor. |
926037-48-1 |
Radotinib(IY-5511) |
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cis a novel and selective BCR-ABL1 tyrosine kinase inhibitor with IC50 of 34 nM for wild-type BCR-ABL1 kinase. |
944842-54-0 |
Decernotinib(VX-509) |
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Decernotinib(VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki of 2.5 nM; IC50 is 50-170 nM in cellular assays. |
1092499-93-8 |
NVP-BSK805 |
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NVP-BSK805 is a potent and selective ATP-competitive JAK2 inhibitor with IC50 of 0.5 nM; >20-fold selectivity towards JAK1, JAK3 and TYK2. |
457081-03-7 |
Pyridone 6 |
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Pyridone 6 are highly active JAK inhibitors of JAK1 (mice), JAK2 and Tyk2 IC50 15 1 nM and nM,1 nM, respectively, Ki of JAK3 is 5 nM, very low affinity to other protein tyros... |
936091-14-4 |
TG101209 |
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TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM, less potent to Flt3 and RET with IC50 of 25 nM and 17 nM in cell-free assays, ~30-fold selective for JAK2 than JAK3,... |
1092499-93-8 |
NVP-BSK805 2HCl |
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NVP-BSK805 2HCl is a potent and selective ATP-competitive JAK2 inhibitor with IC50 of 0.5 nM,>20-fold selectivity towards JAK1, JAK3 and TYK2 |
1229236-86-5 |
LY2874544 |
more... |
LY2784544 is a potent JAK2 inhibitor with IC50 of 3 nM, effective in JAK2V617F, 8- and 20-fold selective versus JAK1 and JAK3. Phase 2 |